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At
Risk States
Includes:
Schizophrenia,
Schizoaffective Disorder, Schizophreniform,
Psychosis (NOS)
| Clinical
Research |
Definitions |
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Clinical
Research At Risk
How
to use this page: There are some research
studies at UNC that target 'at risk' states.
Below are the names and brief descriptions
of each study. If you see a study that may
apply to you, click on the link and get
further details on the study and contact
information.
| PRIME
Research Programs
and
Website |
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| PRIME
Website |
| PREDICT:
Prodromal Research for Early Detection
in a Collaborative Team
The goal of this project
is to improve identification of individuals
who will develop schizophrenic psychosis
at the initial prodromal stage of
illness, prior to the onset of the
full syndrome. Accurate identification
of prodromal individuals offers what
may be perhaps the field’s best
hope for developing more effective
treatment strategies, including secondary
prevention of this typically devastating
illness.
Ages:
14-30
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Conte Center Website
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| Conte
Center: Mapping Brain Functions in
Adolescents
This
study is targeted towards subjects
who may be at risk for schizophrenia
by virtue of having a first-degree
relative (parent or sibling) that
has been diagnosed with a psychotic
disorder (schizophrenia and/or schizoaffective
disorder). We are interested in comparing
the normal changes in brain structure
and function that occur during puberty
in those with and without a first-degree
relative with a psychotic disorder.
This
study involves MRI brain imaging (where
magnets are used to take pictures
of the brain) and electrophysiology
studies to measure brain activity.
These are safe, routine medical procedures.
Age:
9-18 |
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Early
Brain Development in the Children
of Mothers with Schizophrenia
Adults with schizophrenia have changes
in brain structure, including enlargement
of the lateral ventricles. We are
conducting a prospective, longitudinal
study to determine if the children
of women with schizophrenia have changes
in fetal and neonatal brain structure,
especially in the lateral ventricles.
Ages:
18 or older |
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MVM:
Fetal Mild Ventriculomegaly Study
We are conducting a prospective, longitudinal
study of outcome to determine if children
with fetal MVM have a higher risk
for childhood neurodevelopmental delays
than children without MVM.
Ages:
18 or older |
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