Education:
B.A., Biology: University of Illinois
M.D., University of Illinois Medical Center
Residency, Psychiatry: University of North Carolina at Chapel Hill, School of Medicine
Fellowship, Clinical Associate: National Institute of Mental Health

Summary Statement:
Dr. James Garbutt is interested in the psychopharmacology of alcoholism and mood and also anxiety disorders. He is the Medical Director of our Alcohol and Substance Abuse Program and runs a clinic that evaluates and treats individuals with alcoholism, other drug problems, and psychiatric illnesses. He also runs a clinic for psychopharmacological treatment of mood and anxiety disorders. His group generally has several clinical trials of new medications for alcoholism running. Dr. Garbutt is a member of the Committee on the Protection of the Rights of Human Subjects (IRB for the School of Medicine). He works with several other physicians to provide electroconvulsive therapy to patients at UNC Hospitals.

Representative Publications:
1. Kampov-Polevoy AB, Alterman A, Khalitov E, Garbutt JC. Sweet preference predicts mood altering effect of and impaired control over eating sweet foods. Eating Behaviors (in press).

2. Garbutt JC, Kranzler HR, O’Malley SS, Gastfriend DR, Pettinatit, HM, Silverman BI, Loewy JW, Ehrich EW for the Vivitrex Study Group. Efficacy and tolerability of long-acting, injectable naltrexone for alcohol dependence: a randomized, controlled trial. Journal of the American Medical Association 293:1617-1625, 2005.

3. Anton R, Kranzler H, O’Malley S, Pettinati H, Garbutt JC, et al. A multisite dose ranging study of nalmefene in the treatment of alcohol dependence. Journal of Clinical Psychopharmacology 24:421-428, 2004.

4. Flannery BA, Garbutt JC, Cody MW, Renn W, Grace K, Osborne M, Crosby K, Morreale M, Trivette A. Baclofen for alcohol dependence: a preliminary open-label study. Alcoholism: Clinical and Experimental Research 28:1517-1523, 2004.

5. Kampov-Polevoy AB, Garbutt JC, Khalitov E. Family history of alcoholism and response to sweets. Alcoholism: Clinical and Experimental Research 27:1743-1749, 2003.

6.Garbutt JC, West SL, Carey TS, Lohr KN, Crews FT. Pharmacological treatment of alcohol dependence: a review of the evidence. Journal of the American Medical Association 281:1318-1325, 1999.