John H. Gilmore, M.D.

Education:

B.A., University of Virginia, 1981

M.D., University of North Carolina at Chapel Hill, 1985

Intern, Department of Surgery, Graduate Hospital, Philadelphia, Pennsylvania, 1986

Resident, Psychiatry, New York Hospital-Cornell Medical Center, Payne-Whitney Clinic, 1989

Research Fellow, Psychiatry, University of North Carolina at Chapel Hill, 1991

Summary Statement:

Dr. Gilmore is a Professor of Psychiatry and is the Vice Chair for Research and Scientific Affairs.  He is Director of the UNC Schizophrenia Research Center, an NIMH-sponsored Conte Center for the Neuroscience of Mental Disorders, and Director of the Clinical Neuroscience and Pharmacology Research Fellowship Program. 

Dr. Gilmore is also a member of the UNC Neurodevelopmental Disorders Research Center and the Curriculum in Neurobiology.  Clinically, Dr. Gilmore is active with the Schizophrenia Treatment and Evaluation Program, both in the Outpatient Clinic and on the Psychotic Disorders Inpatient Unit.

Research Interests:

Dr. Gilmore is Director of the Center for Excellence in Community Mental Health.  His research focuses on brain development and risk for schizophrenia and other neurodevelopmental disorders. One line of research involves the study of prenatal and early postnatal brain development in normal children and in children at risk for neurodevelopmental disorders and schizophrenia, using ultrasound and magnetic resonance imaging.  He also studies mechanisms through which maternal infection during pregnancy alters cortical neuron development.

Representative Publications:

1. Gilmore JH, van Tol J, Lewis-Streicher H, Williamson K, Cohen SB, Greenwood R, Charles CR, Kliewer MA, Whitt JK, Silva SG, Hertzberg BS, Chescheir NC. Outcome in children with fetal isolated mild ventriculomegaly: A case series. Schizophrenia Research 2001; 48: 219-226.
2. Gilmore JH, Gerig G, Specter B, Charles HC, Wilber JS, Hertzberg BS, Kliewer MA. Neonatal cerebral ventricle volume: a comparison of 3D ultrasound and magnetic resonance imaging. Ultrasound in Medicine and Biology 2001; 27:1143-1146.
3. Zhai G, Lin W, Wilber K, Gerig G, Gilmore JH. Comparisons of regional white matter diffusion in healthy neonates and adults using a 3T head-only scanner. Radiology 2003; 229: 673-681.
4. Gilmore JH, Jarskog LF, Vadlamudi S, Lauder JM. Prenatal infection and risk for schizophrenia: IL-1ß, IL-6, and TNFa inhibit cortical neuron dendrite development. Neuropsychopharmacology 2004; 29: 1221-1229.
5. Gilmore JH, Zhai G, Wilber K, Smith JK, Lin W, Gerig G. 3T magnetic resonance imaging of the brain in newborns. Psychiatry Research Neuroimaging 2004; 132:81-85.
6. Gilmore JH, Jarskog LF, Vadlamudi S. Maternal poly I:C exposure during pregnancy regulates TNFa, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat. J Neuroimmunology 2005; 159: 106-112.